A little more than a year ago, we launched Ansa Biotechnologies’ very first commercial DNA Synthesis products: Ansa Clonal DNA and Ansa DNA Fragments up to 900 bp long. It was a critical milestone in the life of our company, but we knew that the real magic for customers would come when we could deliver significantly longer, high-quality synthetic DNA constructs..
Today, we are proud to announce the commercial availability of our high-quality clonal DNA products as long as 50 kb — almost 100-fold the size of where we began! This 50 kb synthetic DNA is manufactured using our proprietary enzymatic DNA synthesis platform, ensuring the same accuracy, reliability, and sequence fidelity that customers have come to expect from Ansa Biotechnologies.. And it’s available at market-beating prices, as little as 28 cents per base pair with turnaround times less than 25 business days.
If you’ve read the Ansa blog before, you probably know that our company was founded by scientists who got so frustrated by the inability to get the DNA required for their experiments that they set out to develop a novel DNA synthesis technology — one that would expand access to far more sequence designs and perform more reliably than conventional approaches. The platform they created is the reason that Ansa can deliver DNA no one else can.
Today’s most widely used DNA synthesis services generally can’t produce constructs longer than 10 kb. That’s a huge limitation for scientists, who must either assemble shorter fragments themselves—an error-prone, time-consuming process—or abandon the longer sequences they need for critical synthetic biology and genetic engineering research.
Our enzymatic DNA synthesis technology overcomes these barriers, enabling us to produce ultra-long and complex synthetic DNA constructs that often trigger rejections from other vendors. It reflects our steadfast commitment to the scientific community. You shouldn’t have to compromise your research because of a vendor’s limitations. If you need long or complex DNA to move your work forward, you should be able to count on your synthetic DNA vendor to deliver. That’s why we introduced the Ansa On-Time Guarantee, ensuring that customers receive their orders in full and on time or the whole thing is free.
Customer Feedback
Our 50 kb DNA products have been available to a small number of scientists through an early access program. Check out what some of them had to say about their experience:
“Ansa has provided us with extremely long and complex constructs we couldn’t get anywhere else. For these types of sequences, as long as 50 kb, other providers often reject or quote an extremely long ETA. Without Ansa, we couldn’t obtain them so efficiently, affordably, and reliably — or at all!”
— Molly Gasperini, Allen Institute
“Our experience with Ansa Biotechnologies has been excellent. The company successfully delivered a set of complex, repetitive sequences up to 41 kb that several other companies had declined to synthesize, all in about half the time of current industry standards. The Ansa team is responsive, easy to work with, and consistently follows through.”
— George Church, Harvard Medical School and MIT
“The construct was perfect — exactly what I needed, and I could not have gotten this to work without your help.”
— Liyam Chitayat, MIT
“Ansa has been a consistent, responsive, and reliable partner who Terrain has utilized to great effect to deliver us highly complex DNA constructs that enable us to build complex and long mRNA sequences. As the proteins used in medicine get larger and more complex, so too do the sequences that encode them. Our partnership with Ansa, and particularly their 7.5 kb – 50 kb clonal gene offering, enables us to push the limits of mRNA design and manufacturing. It has been a pleasure working with Ansa and it always feels like a true partnership.”
— Aaron Larsen, Terrain Bio
Ansa On-Time Guarantee
We’re upending the entire synthetic DNA ordering process. Get your complete order on time, or it’s free. Learn more.
Give Ansa a Try
With the availability of 50 kb clonal DNA, scientists can explore entirely new avenues of research in applications such as synthetic genomics, metabolic engineering, agricultural research, and next-generation cell and gene therapies. Whether you’re building a new chassis organism, designing an entire viral vector from scratch, or scaling up from lab bench to biomanufacturing, Ansa’s long DNA capabilities ensure you won’t be held back by synthesis constraints.
All of Ansa’s DNA products are made in the USA and verified with highly accurate long-read sequencing and a proprietary informatics pipeline.
We are ready to power your next bold experiment! Don’t let your research vision be limited by the size of your DNA constructs. Learn more about how to access ultra-long DNA with Ansa today.