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Enzymatic DNA synthesis enters new phase

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“But more generally, these short sequences are just a stepping stone toward being able to generate the long sequences that are currently out of reach with chemical synthesis. ‘We’re trying to make thousand-mers and make those into genes,’ says Arlow. Beyond synthetic biology, this could also help accelerate the production of nucleic acid-based vaccines or generate the lengthy strands of DNA needed for targeted rewriting of the genome with CRISPR through homology-directed recombination.”

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