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Technology feature – How to build a genome

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“The standard technique, called phosphoramidite synthesis, is decades old and struggles to produce sequences longer than about 200 bases; anything bigger must be created by linking the fragments together. Enzymatic synthesis methods are a promising alternative. In 2018, for instance, researchers led by synthetic biologist Jay Keasling and his then-PhD student Daniel Arlow at the University of California, Berkeley, demonstrated a process using enzymes…”

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